Low Dose Naltrexone
Low Dose Naltrexone
Gentle immune system modulation, inflammation support, and mood balance
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Gentle immune system modulation, inflammation support, and mood balance
What is LDN ?
Low Dose Naltrexone (LDN) is a compounded, low-dose formulation of the opioid receptor antagonist naltrexone. At lower dosages, it works differently than standard naltrexone—modulating the immune system and reducing chronic inflammation. It is used off-label for a range of conditions including autoimmune diseases, chronic pain, fibromyalgia and mood disorders. At low doses, LDN temporarily blocks opioid receptors, which causes the body to upregulate endorphin production—creating lasting anti-inflammatory and immune-calming effects.
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FAQ
How does it work?
How does it work?
Low Dose Naltrexone functions through transient opioid receptor blockade, which stimulates the body’s natural healing response
What are the side effects of LDN ?
What are the side effects of LDN ?
Common (initial/transient):
- Vivid dreams or sleep disturbances (typically improve in 7–10 days)
- Mild headache or nausea
- Temporary increase in autoimmune symptoms (rare, resolves)
Less Common:
- Anxiety or mood changes
- Restlessness at night
- Hypothyroid symptoms if thyroid dose isn’t adjusted (in Hashimoto’s)
Note: LDN should not be taken with opioid pain medications. It may block their effect.

